Research

JCOIN includes 13 clinical research centers (“Research Hubs”), that are studying evidence-informed approaches to ensure quality care is provided to individuals with opioid use disorder in justice settings, and two resource centers that conduct complementary studies and provide supportive infrastructure: the Coordination and Translation Center (CTC) and the Methodology and Advanced Analytics Resource Center (MAARC).

JCOIN Studies

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Publications Library

Browse JCOIN articles, protocols, presentations, and more.

Research Translation

Breakdowns of research regarding substance use disorders within health and justice settings.

JCOIN Studies

Each JCOIN study brings researchers together with justice and health stakeholders in five or more communities to address gaps in opioid use disorder treatment and related services. Their work engages a wide range of justice settings, including jails, prisons, community corrections, problem-solving courts, and juvenile justice agencies. The studies evaluate behavioral interventions, digital therapeutics, comprehensive patient-centered treatments, and delivery of medications for opioid use disorder (MOUD) throughout the United States.

In 2018-2020, JCOIN supported 15 accelerator supplement projects, which included short-term studies and surveys.

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Standard vs Adaptive Recovery Management Checkups (033)

Principal Investigator(s): Michael Dennis, Christine Grella

This study is comparing the effectiveness of the Recovery Management Checkups (RMC) model, an evidence-based intervention that provides regular, fixed schedule check-ups to support treatment retention and recovery, and an adaptive model (RMC-Adapted) that tailors checkup frequency and intensity to individuals’ needs. Each condition offers justice-involved individuals referral or assertive linkage to a designated treatment provider upon release from jail.

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Evaluation of Massachusetts State-Mandated Pilot of MOUD in Jails (032)

Principal Investigator(s): Liz Evans, Peter Friedmann

A 2018 Massachusetts law (“Chapter 208”) established a 4-year pilot program to expand the use of all FDA-approved forms of medications for opioid use disorder (MOUD) at five county jails; two additional jails voluntarily joined this pilot. The law stipulates that MOUD be maintained in individuals who were already receiving it prior to detention; initiated prior to release from jail when appropriate; and continued in the community via facilitated linkages to local services after release. The Massachusetts Hub will conduct a longitudinal treatment outcome study of individuals in these jails to examine MOUD initiation, engagement and retention, as well as fatal and non-fatal overdose and recidivism. The study will also identify strategies associated with the successful implementation of MOUD and inform the development of future strategies to address opioid use disorder in jails nationwide.

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Implementing an Opioid Court Model (031)

Principal Investigator(s): Milton Wainberg, Ned Nunes, Katherine Elkington, Ph.D.

This study is evaluating strategies to implement New York’s new opioid court model (OCM) in ten counties across the state. New York’s OCM was developed by the Unified Court System and provides practice guidelines for drug courts to reduce overdose, decrease recidivism, and improve service delivery and linkages to medications for opioid use disorder (MOUD) for justice-involved individuals across the state. The goal of the study is to develop, evaluate, and refine implementation strategies to support the OCM practice guidelines to be scaled up across New York.

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MOUD + Pre-Treatment Telehealth for Women Leaving Jail (030)

Principal Investigator(s): Michele Staton

This study will evaluate the effectiveness of initiating treatment services through telehealth and peer navigation for justice-involved women with opioid use disorder (OUD) as they transition from jail to the community. Through these services, participants will be able to engage with community health providers and peer navigators prior to release.

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Dynamic Network Collaboration Study (029)

Principal Investigator(s): Bruce Taylor, Kayo Fujimoto

The NORC at the University of Chicago, in partnership with the University of Texas Health Science Center at Houston, is conducting a longitudinal study to measure how collaborations and partnerships between researchers and practitioners within the JCOIN network change over time. The study will collect annual data over five years via online surveys and will be supplemented by automated web scraping to capture members’ publications, chapters, books, presentations, reports, and grants. Capturing changes in JCOIN members’ collaboration, productivity, publications, and grant activities will offer NIDA an opportunity to understand how collaborations within the JCOIN network improve when supporting a large network of substance abuse researchers and practitioners.

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National Longitudinal Jail/Prison Survey (028)

Principal Investigator(s): John Schneider, Bruce Taylor

Despite the effectiveness of medications for opioid use disorder (MOUD), there is a lack of information about what is currently available, accessible, and used throughout the jail and prison systems of the US. To better address this gap, the NORC at the University of Chicago will study how prisons and jails across 24 justictions are addressing opioid use disorder.

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AmeriSpeaks In-Depth Public Opinion Survey on Opioids (027)

Principal Investigator(s): Bruce Taylor

The NORC at the University of Chicago is conducting a comprehensive study to measure the public’s view of policies, practices, attitudes and laws related to addressing opioids in justice settings across the U.S. This study builds on the topics from the JCOIN AmeriSpeak Brief Opioid Stigma Survey (026) and will also assess how support varies based on personal experiences with opioids or knowing someone who struggled with an OUD and variations by type of opioid and respondent characteristics.

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AmeriSpeak Brief Opioid Stigma Survey (026)

Principal Investigator(s): Bruce Taylor

To assess how stigma changes overtime, the NORC at the University of Chicago is conducting a study to measure public support for opioid use disorder (OUD) treatment, assess stigma associated with OUD, and perceptions of criminality around OUD. This study will use a nationally representative survey panel and will administer short surveys twice a year for a total of five years. The data collected from this study will allow for a better understanding of the public’s opinion on issues related to OUD, stigma, and the justice system and how perceptions change over time.

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Mapping Federal Opioid Investments (025)

Principal Investigator(s): Colleen Grogan

The University of Chicago is conducting a large-scale environmental scan of federally funded substance use-related initiatives and resources to understand how funds and resources are distributed across states. The study will also explore urban and rural differences, differences across areas based upon local drug-use epidemiology and availability of service resources and how federal funds are addressing opioid use disorders and other emerging drug-related challenges.

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Supportive Social Networks and Outcomes (024)

Principal Investigator(s): John Schneider, Carrie Oser

Social support networks have been an invaluable tool to combat addiction and other health interventions. The concept of social support networks as a powerful force in the health of substance users is well documented. Effective substance use disorder (SUD) and opioid use disorder (OUD) treatment approaches have been effectively combined with the inclusion of naturally-occurring support persons. The concept of organic social support has been under-utilized for retaining community members in SUD treatment programs.

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Re-Entry: Social Networks and Opioid Use (023)

Principal Investigator(s): John Schneider

Diverse communities enter the justice system, exit and re-enter to create a complex circulation driven by a number of social and structural factors. Often ignored are important social interactions that drive opioid use disorder (OUD) or methamphetamine use. Social learning and differential association theories hold that risky behaviors, including rationalizations for them, diffuse through social networks of close ties. Furthermore, network members influence behavior by virtue of the behavioral example they provide, the normative pressures they exert, and perceptions of these influences. If we understand how OUD/meth or recovery/renewed use moves through networks and their local geographic contexts, we will be able to develop new interventions, and determine previously unobserved mechanisms as to why interventions may fail or have success.

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Predicting the Next Overdose (022)

Principal Investigator(s): Harold Pollack, PhD

The University of Chicago is developing open-source software that can be used by researchers and practitioners to predict overdose and re-offending risk of their population. This project will use large administrative datasets and machine-learning technology to develop a framework for transparent predictive models and simulations to help identify people at highest risk and how populations will benefit from interventions, and explore the likely policy impact of observed relationships among emerging trends to improve outcomes.

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MOUD Access and Place-Based Policies (021)

Principal Investigator(s): Marynia Kolak

Across the country, various public health interventions, opioid use policies, and criminal justice policies have emerged in response to the opioid epidemic in recent years. Many of the policies help improve access to medications for opioid use disorder (MOUD) and related services. However, the impact of improving access to these resources on health outcomes can vary substantially in different local contexts under various policies.

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Optimal Distance to Treatment Services (020)

Principal Investigator(s): Marynia Kolak

The University of Chicago is developing an agent-based network model (ABNM) framework to study location-specific evolution and dynamics of opioid use disorder (OUD) in justice settings. The Justice Community Circulation Model framework is designed to help researchers and practitioners explore underlying mechanisms, epidemiological processes and interactions, such as the health and mortality pathways of individuals who experience non-fatal overdose or who initiate treatment, among justice-involved individuals with OUD.

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Social/Spatial Inequities and OUD/HCV Outcomes (019)

Principal Investigator(s): Marynia Kolak, Jonathan Ozik

Access to treatment and medication for opioid use disorder (MOUD) is essential for reducing HIV and HCV transmissions. However, the spatial distribution of the resources for treatment and medication is a result of various social factors, which can include potential inequities.

To demonstrate the utility of a spatial perspective in evaluating access to MOUD resources, the University of Chicago and Argonne National Laboratory will use a simulation approach to evaluate how treatment and intervention locations affect HIV and HCV transmissions.

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In Silico JCOIN Trial Models (018)

Principal Investigator(s): John Schneider

Computational analogues of the JCOIN clinical research centers, so called in silico clinical trials, in the form of data-driven, agent-based network models (ABNMs), can provide a variety of simulation-based analyses to investigate longer-term health outcomes beyond the clinical trial timelines. Building on the Justice-Community Circulation Model (JCCM), the University of Chicago will apply the JCCM framework to develop in silico versions of JCOIN’s clinical research trials to run computational trials such as optimizing cross-study combinations of interventions or tracking additional and emerging outcome.

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Justice-Community Circulation Model (017)

Principal Investigator(s): John Schneider

The University of Chicago is developing an agent-based network model (ABNM) framework to study location-specific evolution and dynamics of opioid use disorder (OUD) in justice settings. The Justice Community Circulation Model framework is designed to help researchers and practitioners explore underlying mechanisms, epidemiological processes and interactions, such as the health and mortality pathways of individuals who experience non-fatal overdose or who initiate treatment, among justice-involved individuals with OUD.

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Developing a Communication Effectiveness Measure (016)

Principal Investigator(s): Faye Taxman, Xiaoquan Zhao

George Mason University is conducting a study to test and refine a newly developed instrument designed to measure perceived effectiveness of communication products. The intention of the study is to provide the Network with an instrument that can be used to measure the impact of all JCOIN communication products. The study team is piloting the instrument with two sites, the Iowa Department of Corrections and the Arizona Supreme Court. The goal of the study is to develop and validate a communication effectiveness instrument to measure the potential impact of training, and technical assistance related to research to practice issues.

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Systematic Literature Reviews (015)

Principal Investigator(s): Michael Dennis

Policies aimed at addressing the high rates of opioid overdose have prioritized increasing access to medications for treatment of opioid use disorder (MOUD). Numerous barriers exist to providing MOUD within the criminal justice system and/or to justice-involved populations. The aim of this study was to conduct a scoping review of the peer-reviewed literature on implementation of MOUD within criminal justice settings and with justice-involved populations.

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Geospatial Analytics with Drug Arrest Data (014)

Principal Investigator(s): Eric Wish, Erin Artigiani, Kathleen Stewart

The University of Maryland’s Center for Substance Abuse Research (CESAR) established the Coordinating Center for the National Drug Early Warning System (NDEWS) for NIDA in 2014. NDEWS is a public health surveillance system that generates critically needed information about drugs and their public health consequences so that rapid, informed, and effective public health responses can be developed. Over the past four years, the Coordinating Center has developed national and international collaborations to support the ability to identify, monitor, and follow-up on emerging drugs and changing drug trends. These capabilities will be used in studies to link scientists and practitioners from the justice and public health fields and to generate resources and tools to support improvements in both fields.

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