ACTION: Addressing Risk through Community Treatment for Infectious Disease Now (042)

Improving HIV and opioid use disorder (OUD) management and implementation for justice-involved individuals requires effective approaches to screening, linkage, and adherence to integrated services across community agencies and service providers. Community reentry represents a critical opportunity to link individuals to HIV prevention, treatment, and OUD service providers. The Yale University JCOIN Research Center is conducting…

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Testing XR:NTX vs XR:B (Sublocade) (035)

This study is conducting a large multisite trial to compare the effectiveness of extended-release buprenorphine (Sublocade, XR-B) to extended-release naltrexone (XR-NTX). The trial will enroll individuals prior to release from jail and randomize to either medication option. The first dose of medication will be administered prior to release, with an additional 24 weeks of treatment received in the community.

Participating jails are located in Connecticut, Delaware, New Hampshire, New Jersey and Oregon. The study will measure retention in treatment, and opioid and other substance use outcomes between the two medication conditions, as well as a sample of individuals who opt for other treatment options (“treatment as usual”).

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