This study analyzed the attitudes of young adults (19-29 years) in the United States toward persons with opioid use disorder (OUD) through the lens of social stigma, discrimination, and policy attitudes. On average, although young adults supported treatment-oriented policies for those with opioid use disorder, they also endorsed moderate levels of stigma and discrimination. Increased stigma and discrimination were also associated with older age and less familiarity or personal experience with OUD.